Increase GLP-1 Agonists Naturally

Key Takeaways:

  • GLP-1 agonists regulate appetite, insulin production, and blood sugar levels.
  • Regular exercise and quality sleep maintain optimal GLP-1 levels.
  • High-protein, low-carb diets effectively boost GLP-1 levels.
  • Butter, ghee, tallow, and egg yolks are ideal for stimulating GLP-1.
  • Gut health, supported by probiotics and fiber, influences GLP-1 production.

Understanding GLP-1 Agonists

glucagon

What are GLP-1 Agonists?

GLP-1 (glucagon-like peptide-1) agonists are hormones that play a role in the body’s metabolism.

They help control blood sugar levels, manage appetite, and encourage insulin release. Their ability to promote satiety makes them valuable in weight management and metabolic health.

Health Benefits of GLP-1 Agonists

GLP-1 agonists offer more than just appetite control. They enhance insulin sensitivity, which is important for blood sugar management.

Additionally, they support cardiovascular health by improving endothelial function and reducing inflammation.

Foods That Boost GLP-1 Levels

superfoods

High-Protein Foods

Protein is a key nutrient for stimulating GLP-1 release. Foods such as eggs, meat, and fish are excellent sources of protein that help increase GLP-1 levels.

Having a high protein breakfast can significantly keep you feeling full throughout the day.

Healthy Fats

Butter, ghee, tallow, and egg yolks are not only rich in essential nutrients but also stimulate GLP-1. Olive oil and avocado oil also offer benefits.

Adding these fats to your diet, whether through cooking or as part of meals, helps maintain steady GLP-1 levels.

Try to avoid eating large amounts of fat and carbohydrates at the same time. That is never a good combination.

Fiber-Rich Foods

Soluble fiber can stimulate GLP-1 production. Vegetables, fruits, and legumes are sources of soluble fiber that stimulate GLP-1 release.

Probiotic-Rich Foods

Gut health is closely linked to GLP-1 production. Consuming probiotic-rich foods such as yogurt, kefir, and sauerkraut supports a healthy gut microbiome, which in turn enhances GLP-1 secretion.

Fermented foods are particularly effective in this regard and can be easily added to your daily diet.

Lifestyle Changes to Naturally Boost GLP-1

fun exercise running at beach

Regular Exercise

Exercise is a powerful tool for boosting GLP-1 levels. Both aerobic exercise, like walking or cycling, and resistance training, such as weight lifting, stimulate the release of GLP-1.

Regular physical activity enhances hormone production and improves overall metabolic health.

Adequate Sleep

Quality sleep is necessary for maintaining healthy GLP-1 levels. Poor sleep disrupts hormone production and negatively affects appetite regulation.

Aim for 7-9 hours of uninterrupted sleep per night to support optimal GLP-1 levels.

Managing Stress

Chronic stress interferes with GLP-1 production, leading to imbalances in hunger and insulin levels.

Practices like meditation, deep breathing, or yoga can help maintain stable GLP-1 levels.

The Role of Gut Health in GLP-1 Production

Increase GLP-1 Agonists Naturally

Importance of Gut Microbiota

The gut microbiota plays a significant role in GLP-1 production. A healthy and diverse gut flora is necessary for the optimal secretion of GLP-1.

Diets rich in fiber and probiotics support gut health, leading to increased GLP-1 levels.

Prebiotics and Probiotics

Prebiotics and probiotics are key for a healthy gut, which in turn supports GLP-1 production. Foods like garlic, onions, and asparagus are excellent prebiotic sources, while fermented foods provide beneficial probiotics.

These elements help create a gut environment conducive to GLP-1 release.

Supplements to Enhance GLP-1 Levels

Berberine

Berberine is a supplement known to increase GLP-1 levels. It also improves insulin sensitivity and supports metabolic health.

Recommended dosages should be followed, and consulting a healthcare provider before starting any supplement regimen is advisable.

Omega-3 Fatty Acids

Omega-3 fatty acids, found in cod liver oil, support GLP-1 production. They also offer anti-inflammatory benefits that contribute to overall health.

Other Potential Supplements

Supplements such as inositol, curcumin, and chromium have also been linked to increased GLP-1 levels.

The brilliant doctors and scientists at Pendulum Therapeutics, Inc. have formulated a unique solution in the new GLP-1 Probiotic.

Increase GLP-1 Agonists Naturally
Increase GLP-1 Agonists Naturally
Increase GLP-1 Agonists Naturally
Increase GLP-1 Agonists Naturally

Possible Side Effects

Overstimulating GLP-1 can lead to side effects such as nausea or gastrointestinal discomfort.

Gradually approaching dietary and lifestyle changes and monitoring the body’s response is essential.

Consultation with Healthcare Providers

Before making significant changes to your diet or lifestyle consult a healthcare provider. They can provide personalized advice and ensure that any changes are safe and appropriate for your health status.

FAQ:

What is the role of GLP-1 in weight loss?
GLP-1 helps regulate appetite and enhances insulin sensitivity, making it easier to manage weight.

Can increasing GLP-1 naturally help manage diabetes?
Yes, by improving insulin sensitivity and controlling blood sugar levels, natural methods to boost GLP-1 can be beneficial for diabetes management.

Are there any foods that reduce GLP-1 levels?
Highly processed foods and those high in sugar can negatively affect GLP-1 levels.

How long does it take to see benefits from these lifestyle changes?
Improvements in GLP-1 levels can vary, but many people start noticing benefits within a few weeks of making dietary and lifestyle changes.

Is it safe to take GLP-1 boosting supplements?
Healthy food should always be the primary source and supplements by definition secondary. Berberine is generally safe but should be taken under the guidance of a healthcare provider.

Research


Al-Asmakh, M., Anuar, F., Zadjali, F., Rafter, J. and Pettersson, S., 2012. Gut microbial communities modulating brain development and function. Gut Microbes, [online] 3(4), pp.366–373.
https://doi.org/10.4161/gmic.21287.

Araj-Khodaei, M., Ayati, M.H., Azizi Zeinalhajlou, A., Novinbahador, T., Yousefi, M., Shiri, M., Mahmoodpoor, A., Shamekh, A., Namazi, N. and Sanaie, S., 2023. Berberine-induced glucagon-like peptide-1 and its mechanism for controlling type 2 diabetes mellitus: a comprehensive pathway review. Archives of Physiology and Biochemistry, [online] pp.1–8.

Adam, T.C.M., Jocken, J. and Westerterp‐Plantenga, M.S., 2005. Decreased Glucagon‐like Peptide 1 Release after Weight Loss in Overweight/Obese Subjects. Obesity Research, [online] 13(4), pp.710–716.

Ahren, B., Larsson, H. and Holst, J.J., 1997. Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in noninsulin-dependent diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 82, pp.473–478.

Ben-Harchache, S., Roche, H. M., Corish, C. A., & Horner, K. M. (2021). The Impact of Protein Supplementation on Appetite and Energy Intake in Healthy Older Adults: A Systematic Review with Meta-Analysis. Advances in Nutrition, 12(2), 490-502. https://doi.org/10.1093/advances/nmaa115

Deacon, C.F., 2004. Therapeutic Strategies Based on Glucagon-Like Peptide 1. Diabetes, [online] 53(9), pp.2181–2189.

Gupta, V., 2013. Glucagon-like peptide-1 analogues: An overview. Indian Journal of Endocrinology and Metabolism, [online] 17(3), p.413.

Gutzwiller, J.-P., Göke, B., Drewe, J., Hildebrand, P., Ketterer, S., Handschin, D., Winterhalder, R., Conen, D. and Beglinger, C., 1999. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut, [online] 44(1), pp.81–86.

Holst, J.J., Deacon, C.F., Vilsbøll, T., Krarup, T. and Madsbad, S., 2008. Glucagon-like peptide-1, glucose homeostasis and diabetes. Trends in Molecular Medicine, [online] 14(4), pp.161–168.

Holst, J.J., 2007. The Physiology of Glucagon-like Peptide 1. Physiological Reviews, [online] 87(4), pp.1409–1439.
https://doi.org/10.1152/physrev.00034.2006.

Iwase, Y., Kamei, N. and Takeda-Morishita, M., 2015. Antidiabetic Effects of Omega-3 Polyunsaturated Fatty Acids: From Mechanism to Therapeutic Possibilities. Pharmacology & Pharmacy, [online] 06(03), pp.190–200.

Karhunen, L.J., Juvonen, K.R., Huotari, A., Purhonen, A.K. and Herzig, K.H., 2008. Effect of protein, fat, carbohydrate and fibre on gastrointestinal peptide release in humans. Regulatory Peptides, [online] 149(1–3), pp.70–78.

Kelly, A.S., Rudser, K.D., Nathan, B.M., Fox, C.K., Metzig, A.M., Coombes, B.J., Fitch, A.K., Bomberg, E.M. and Abuzzahab, M.J., 2013. The Effect of Glucagon-Like Peptide-1 Receptor Agonist Therapy on Body Mass Index in Adolescents With Severe Obesity. JAMA Pediatrics, [online] 167(4), p.355.

Kohanmoo, A., Faghih, S. and Akhlaghi, M., 2020. Effect of short- and long-term protein consumption on appetite and appetite-regulating gastrointestinal hormones, a systematic review and meta-analysis of randomized controlled trials. Physiology & Behavior, [online] 226, p.113123. https://doi.org/10.1016/j.physbeh.2020.113123.

Lim, G.E. and Brubaker, P.L., 2006. Glucagon-Like Peptide 1 Secretion by the L-Cell. Diabetes, [online] 55(Supplement_2), pp.S70–S77.

Müller, T.D., Finan, B., Bloom, S.R., D’Alessio, D., Drucker, D.J., Flatt, P.R., Fritsche, A., Gribble, F., Grill, H.J., Habener, J.F., Holst, J.J., Langhans, W., Meier, J.J., Nauck, M.A., Perez-Tilve, D., Pocai, A., Reimann, F., Sandoval, D.A., Schwartz, T.W., Seeley, R.J., Stemmer, K., Tang-Christensen, M., Woods, S.C., DiMarchi, R.D. and Tschöp, M.H., 2019. Glucagon-like peptide 1 (GLP-1). Molecular Metabolism, [online] 30, pp.72–130.

Pavlisova, J., Horakova, O., Kalendova, V., Buresova, J., Bardova, K., Holendova, B., Plecita-Hlavata, L., Vackova, S., Windrichova, J., Topolcan, O., Kopecky, J. and Rossmeisl, M., 2020. Chronic n-3 fatty acid intake enhances insulin response to oral glucose and elevates GLP-1 in high-fat diet-fed obese mice. Food & Function, [online] 11(11), pp.9764–9775.

Pyke, C. and Knudsen, L.B., 2013. The Glucagon-Like Peptide-1 Receptor—or Not? Endocrinology, [online] 154(1), pp.4–8.

Ritzel, U., Fromme, A., Ottleben, M., Leonhardt, U. and Ramadori, G., 1997. Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum. Acta Diabetologica, [online] 34(1), pp.18–21.

Seino, Y., Maekawa, R., Ogata, H. and Hayashi, Y., 2016. Carbohydrate‐induced secretion of glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1. Journal of Diabetes Investigation, [online] 7(S1), pp.27–32.

Shah, M., Franklin, B., Adams-Huet, B., Mitchell, J., Bouza, B., Dart, L. and Phillips, M., 2016. Effect of meal composition on postprandial glucagon-like peptide-1, insulin, glucagon, C-peptide, and glucose responses in overweight/obese subjects. European Journal of Nutrition, [online] 56(3), pp.1053–1062.
https://doi.org/10.1007/s00394-016-1154-8.

Sivertsen, J., Rosenmeier, J., Holst, J.J. and Vilsbøll, T., 2012. The effect of glucagon-like peptide 1 on cardiovascular risk. Nature Reviews Cardiology, [online] 9(4), pp.209–222.

Yu, Y., Liu, L., Wang, X., Liu, X., Liu, X., Xie, L. and Wang, G., 2010. Modulation of glucagon-like peptide-1 release by berberine: In vivo and in vitro studies. Biochemical Pharmacology, [online] 79(7), pp.1000–1006.

Zhang, Q., Xiao, X., Li, M., Li, W., Yu, M., Zhang, H., Ping, F., Wang, Z. and Zheng, J., 2014. Berberine moderates glucose metabolism through the GnRH-GLP-1 and MAPK pathways in the intestine. BMC Complementary and Alternative Medicine, [online] 14(1).

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